wangxiansong

王显嵩

副教授

研究领域：主要从事基于全基因组及进化角度的肿瘤进化规律挖掘工作

联系邮箱： wangxiansong@mail.sysu.edu.cn

个人简介：

副教授，硕士生导师，生物信息学专业，2021年获得香港中文大学博士学位。于2023年11月加入中山大学。主要从事基于全基因组及进化角度的肿瘤进化规律挖掘工作。近年以第一作者（含共同）先后发表了7篇文章(平均影响因子为24)，包括Annals of Oncology，Cancer Research，Gastroenterology等高水平期刊论文。

现长期诚招博士后，以期共同组建一个相互尊重、平等交流并鼓励创新的科研团队。（具备生物信息学背景亦或想转此方向的有志人士皆可报名）

 

研究成果:

  1. Wang X^, Li X^, Zhang L^, Wong SH, Wang MHT, Tse G, Dai RZW, Nakatsu G, Coker OO, Chen Z, Ko H, Chan JYK, Liu T, Cheng CHK, Cheng ASL, To KF, Plewczynski D, Sung JJY, Yu J, Gin T, Chan MTV, Wu WKK. "Oncogenes expand during evolution to withstand somatic amplification." Annals of Oncology 29, no. 11 (2018): 2254-2260.[IF = 51.769, Q1]
  2. Xiansong Wang^; Frankie T.F. Cheng^; Thomas Y.T. Lam^; Yingzhi Liu; Dan Huang; Xiaodong Liu; Huarong Chen; Lin Zhang; Yusuf Ali; Maggie H.T. Wang; Jun Yu; Tony Gin; Matthew T.V. Chan; William K.K. Wu; Sunny H. Wong. "Stress Hyperglycemia Is Associated With an Increased Risk of Subsequent Development of Diabetes Among Bacteremic and Nonbacteremic Patients." Diabetes Care 45, no. 6 (2022): 1438-1444..[IF=17.152, Q1]
  3. Wang, Xiansong^, Wei Hu^, Xiangchun Li, Dan Huang, Qing Li, Hung Chan, Judeng Zeng, Chuan Xie, Huarong Chen, Xiaodong Liu, Tony Gin, Maggie Haitian Wang, Alfred Sze Lok Cheng, Wei Kang, Ka-Fai To, Dariusz Plewczynski, Qingpeng Zhang, Xiaoting Chen, Danny Cheuk Wing Chan, Ho Ko, Sunny Hei Wong, Jun Yu, Matthew Tak Vai Chan, Lin Zhang, William Ka Kei Wu. "Single-Hit Inactivation Drove Tumor Suppressor Genes Out of the X Chromosome during Evolution" Cancer Research 82, no. 8 (2022): 1482-1491.[IF=13.312, Q1]
  4. Kwong, Thomas NY^, Xiansong Wang^, Geicho Nakatsu, Tai Cheong Chow, Timothy Tipoe, Rudin ZW Dai, Kelvin KK Tsoi, Martin C.S.Wong, GaryTse, Matthew T.V.Chan, Francis K.L.Chan, Siew C.Ng, Justin C.Y.Wu, William K.K.Wu, JunYu, Joseph J.Y.Sung, Sunny H.Wong. "Association between bacteremia from specific microbes and subsequent diagnosis of colorectal cancer." Gastroenterology 155, no. 2 (2018): 383-390..[IF=33.883, Q1]
  5. Zhou, Jiandong^, Xiansong Wang^, Sharen Lee^, William Ka Kei Wu, Bernard Man Yung Cheung, Qingpeng Zhang, and Gary Tse. "Proton pump inhibitor or famotidine use and severe COVID-19 disease: a propensity score-matched territory-wide study." Gut 70, no. 10 (2021): 2012-2013. [IF=31.793, Q1]
  6. Dan Huang^, Xiansong Wang^, Yingzhi Liu, Ziheng Huang, Xiaoxu Hu, Wei Hu, Qing Li, Hung Chan, Yidan Zou, Idy H T Ho, Yan Wang, Alfred S L Cheng, Wei Kang, Ka F To, Maggie H T Wang, Sunny H Wong, Jun Yu, Tony Gin, Qingpeng Zhang, Zheng Li, Jianxiong Shen, Lin Zhang, Matthew T V Chan, Xiaodong Liu, William K K Wu "Multi-omic analysis suggests tumor suppressor genes evolved specific promoter features to optimize cancer resistance." Briefings in Bioinformatics 22, no. 5 (2021): bbab040.[IF=13.994, Q1]
  7. Wu, William KK^, Xiangchun Li^, Xiansong Wang^, Rudin ZW Dai, Alfred SL Cheng, Maggie HT Wang, Thomas Kwong et, Tai C. Chow, Jun Yu, Matthew T.V. Chan, Sunny H. Wong. "Oncogenes without a neighboring tumor-suppressor gene are more prone to amplification." Molecular biology and evolution 34, no. 4 (2017): 903-907.[IF=8.8, Q1]
  8. Dan Huang^, Xiansong Wang^, Ziheng Huang, Yingzhi Liu, Xiaodong Liu, Tony Gin, Sunny Hei Wong, Jun Yu, Lin Zhang, Matthew Tak Vai Chan, Huarong Chen & William Ka Kei Wu "3′ untranslated regions of tumor suppressor genes evolved specific features to favor cancer resistance." Oncogene (2022): 1-11..[IF=8.756, Q1]