药学前沿大讲堂632讲
Chemoproteomics-enabled discovery of covalent ligands for targeted cancer therapy
报告人简介:
Prof Clive Yik-Sham Chung is an Assistant Professor in the School of Biomedical Sciences and Department of Pathology at The University of Hong Kong (HKU). He is also an associate member of State Key Laboratory of Liver Research at HKU and a project team leader (Medicinal Chemistry and Drug Development) in the Center for Oncology and Immunology. He obtained his BSc in chemistry and PhD under the supervision of Prof. Vivian Yam at HKU. He then conducted postdoctoral studies with Prof. Chi-Ming Che on inorganic medicines, Prof Christopher Chang on molecular imaging and Prof. Daniel Nomura on chemoproteomics. Since 2020, he established his own laboratory at HKU, focusing on the development of: (1) chemoproteomics probes to identify new druggable hotspots; (2) molecular probes for investigating cellular redox biology; (3) novel therapeutic covalent ligands for targeted therapy.