药学前沿大讲堂第98讲-Time-dependent alterations of NMDAR function and synaptic plasticity by corticosterone in the adult hippocampus
Time-dependent alterations of NMDAR function and synaptic plasticity by corticosterone in the adult hippocampus
题目:Time-dependent alterations of NMDAR function and synaptic plasticity by corticosterone in the adult hippocampus
报告人:Tak Pan, Wong, Ph.D.
Douglas Mental Health University Institute, Canada
主持人:郑文华 教授
bm11222宝马娱乐网站
时间:2011年8月8日(周一)上午10:00~11:30
地点:中山大学东校区bm11222宝马娱乐网站112会议室
报告人简介:
Tak Pan Wong, PhD, Researcher in Douglas Institute and assistant Professor in Department of Psychiatry, McGill University. One of his research interests is to understand how stress produces abnormality in synaptic transmission, and consequently, impairment in memory formation. Using a combination of electrophysiological, molecular, and proteomic approaches, he will study the molecular mechanism of how stress facilitates a form of hippocampal synaptic plasticity namely long-term depression (LTD). Another major direction of Wong’s laboratory is to study the molecular mechanisms of synaptic plasticity. Research in synaptic plasticity has recently evolved from a focus on physiological processes such as learning and memory to its potential pathological role in producing abnormal synaptic transmission. he has published many papers in top journals such as science, J Biol Chem, Neuron, J Neurosci, Proc Natl Acad Sci USA,